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(R)-3-[1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-(4-isopropyl-5-methylphenyl)benzamide

Product Name (R)-3-[1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-(4-isopropyl-5-methylphenyl)benzamide
Product Code R00002645
Chemical name (R)-3-[1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-(4-isopropyl-5-methylphenyl)benzamide
Synonyms PF-06465469-00;
Impurity
CAS Number 1407966-77-1
Alternate CAS # NA
Molecular form C₃₀H₃₃N₇O₂
Appearance Beige Solid
Melting Point 209-212°C
Mol. Weight 523.63
Storage Refrigerator
Solubility DMSO (Sparingly), Methanol (Sparingly)
Stability
Category Aromatics, Heterocycles, Inhibitors, Pfizer Compounds, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point
Applications (R)-3-[1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-(4-isopropyl-5-methylphenyl)benzamide is a potential covalent inhibitor of Interleukin-2 Inducible T Cell KInase (Itk). Itk is a member of the TEC-kinase family and is associated with the induction of T cell proliferation and drives cytokines through NFATc.
Dangerous Goods Info NA
References
Extra Notes
Documents (MSDS) No Data Available
Keywords Buy 1407966-77-1 | Purchase 1407966-77-1 | Order 1407966-77-1 | 1407966-77-1 supplier | 1407966-77-1 manufacturer | 1407966-77-1 distributor | 1407966-77-1 cost
(R)-3-[1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-N-(4-isopropyl-5-methylphenyl)benzamide
Product Packings
5mg
10mg
25mg
50mg
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